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Predicting Antibiotic Resistance by Whole Genome Sequencing

From the 2020 Joint Annual Meeting (June 29, 2020)
Presented by Daniel Golemboski, PhD
Antibiotic resistance is routinely determined phenotypically in the clinical microbiology lab, but whole-genome sequencing can also be utilized to identify organisms and resistance genes. Sequencing-based tools and methods for the detection of antimicrobial resistance and prediction of susceptibility will be discussed.

At the conclusion of this presentation, participants will be able to:

  1. Describe the current and future role of molecular testing in determination of antibiotic sensitivity.
  2. Compare read-based and assembly-based methods of resistance gene identification.
  3. Discuss the use of functional metagenomics to investigate acquired resistance genes in different environments and human pathogens.

This recorded presentation is P.A.C.E. ® accredited. The instruction level for this activity is Intermediate. One (1) P.A.C.E. ® contact hour and one (1) Florida credit hour in the area of Microbiology/Cytogenetics/Molecular Biology will be awarded to participants. ASCLS P.A.C.E.® is accepted by the ASCP/ASCLS/AGT Board of Certification and all states, including Florida and California, as an approved provider of continuing education for recertification and licensure. ASCLS is an approved provider with CE Broker for Florida licensees.

This intermediate-level program is appropriate for laboratory professionals working in clinical, public health and academic settings.